We were very Nintendo-heavy growing up, so a lot of mine will be obvious:
-Mario (SMA1-3, Sunshine, Galaxy 1+2)
-Zelda (Wind Waker, Twilight Princess, Skyward Sword)
-Mario Kart (Double Dash, Wii)
-Smash Bros (Melee onward)
-Pokemon (Silver, Emerald, Heart Gold)
I'll include some less obvious but very nostalgic ones as well, though:
-Harvest Moon (A Wonderful Life on Gamecube, Animal Parade on Wii, Friends of Mineral Town on GBA)
-Lego Star Wars (both of them on Gamecube)
-EA's Harry Potter (books 2 and 4 on Gamecube, book 2 on PC, book 3 on GBA)
-Big Brain Academy (Wii)
-Yu-Gi-Oh! World Championship Tournament 2004 (GBA)
We also had one of those Plug-N-Play Namco things, came with Pac-Man, Ms. Pacman, Galaxia (different from Galaga??), a racing car game, and the legendary Dig-Dug.
While I'm at it, I may as well list some of the hard nostalgic CD games we had on PC:
-Insaniquarium Deluxe
-Humongous Entertainment Games (Freddy Fish, Pajama Sam, Putt-Putt, etc.)
-Blues Clues: Blues Treasure Hunt
-Crazy Machines
-Adventures with Barbie: Ocean Discovery (anyone? anyone?... no?... yeah that's fair)
Admittedly a lot of those last ones were when I was more ages 3-6, so maybe not as much revisitable nostalgia there...
Oh, but lest I forget some of the classic Flash games:
-MARDEK series
-Fantastic Contraptions
-Stickman Sam
-Pandemic 2
-Red Defender
-Civiballs
-Probably 50 more I'm forgetting
...okay, I should probably shut up for now. But that hopefully gave you enough of an idea, haha.