What is happening with my ROM? It won't open in ZSNES and is REALLY annoying me! I'm not dead.
Does it still open with LM? Have you inserted some blocks or patches? Maybe your ROM is corrupt and ZSNES doesn't load it. Does LM say that the ROM you opened is corrupt? If not, try to open it with an another emulator like Snes9X.
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I should have something witty to put here (even if it's just to update dated info), shouldn't I?
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Try to open your ROM in another emulator to see if it's tied to ZSNES.